Yes, there is no need to change your skin care regimen. You can even apply most anti-aging serums and transparent masks before using Elipsa. However, products that can cause dryness or irritation such as benzoyl peroxide, Retin-A, or harsh acids, should only be applied after using Elipsa. We recommend using Elipsa in the Acne mode on clean, dry skin. Products of your choice may be applied after treatment.